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Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables The encoded protein plays a

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Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables The encoded protein plays aABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed:

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Description

The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2| and expression of this gene may play a role in malignant transformation

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP)

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

each case contains 500 pieces

Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables The encoded protein plays aABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed:

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