Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips Mutations in this gene have

Mutations in this gene have been associated with geroderma osteodysplastica

contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 Lys-9 trimethylation

This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

resulting from an inborn error of endocannabinoid metabolism

Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips Mutations in this gene haveSFXN4 encodes a member of the sideroflexin family. The sideroflexin 4 is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene.