GRK 2(Phospho Ser685) Polyclonal Antibody, 20ul Sampling Tubes Glycosylation at Asn-113 may occur

Glycosylation at Asn-113 may occur at a secondary level

The protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein

Receptor-type tyrosine-protein phosphatase eta encoded by PTPRJ is a member of the protein tyrosine phosphatase (PTP) family

This gene encodes a member of the highly conserved cyclin C subfamily

GRK 2(Phospho Ser685) Polyclonal Antibody, 20ul Sampling Tubes Glycosylation at Asn-113 may occurThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.