S5A2 Polyclonal Antibody, 20ul Metabolic enzymes The C-terminus of the channel

The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting

thereby physically blocking transcription

including the aldehyde form of glucose

These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins

S5A2 Polyclonal Antibody, 20ul Metabolic enzymes The C-terminus of the channelThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).