TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex

and also functions in lymphocyte costimulatory signaling

The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway

TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Several alternatively spliced transcript variantsTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,