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Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing More than 30 loci (SPG1-33)

SKU: 35785073787

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Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing More than 30 loci (SPG1-33)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases

B3GALT1 is a member of the beta-1

Special venting spacers and air slots in the lower cup prevent mesh clogging and liquid overspill

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing More than 30 loci (SPG1-33)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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