AAT Monoclonal Antibody, 50ul[BT-MCA0120] Human Genome Knockout Libraries It is heterogeneously expressed in

It is heterogeneously expressed in the brain

Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation

a disease characterized by abnormalities in cartilage and bone development

and domains IV and VI have a globular conformation

AAT Monoclonal Antibody, 50ul[BT-MCA0120] Human Genome Knockout Libraries It is heterogeneously expressed inThe protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.