p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging guanine nucleotide exchange factors (GEFs)

guanine nucleotide exchange factors (GEFs)

This kinase has also been found to bind and activate protein kinase C-related kinase 2| which suggests its involvement in a regulated signaling process

The protein encoded by this gene is 75% identical to the mouse homolog

and a C-terminal cytoplasmic domain

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging guanine nucleotide exchange factors (GEFs)TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.