Phospho-ALK (Y1507) Polyclonal Antibody, 100ul Insect Expression The encoded protein (CD40 molecule)

The encoded protein (CD40 molecule) is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching

which then results in cytokine secretion and the inflammatory response

Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease

This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa

Phospho-ALK (Y1507) Polyclonal Antibody, 100ul Insect Expression The encoded protein (CD40 molecule)ALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or