Brk Monoclonal Antibody, 50ul Low-speed Centrifuges Mutations in INPP5D are associated

Mutations in INPP5D are associated with defects and cancers of the immune system

This enzyme is a hydroxylase that metabolizes arachidonic acid

Several transcript variants encoding different isoforms have been found for RECK

also called 7B4 and cadherin‑5 (CDH5)

Brk Monoclonal Antibody, 50ul Low-speed Centrifuges Mutations in INPP5D are associatedThe protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded