RGS17 Polyclonal Antibody, 100ul Bottles this protein contains an SH2

this protein contains an SH2 domain flanked by two SH3 domains

Directly binds Holliday junctions

and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals

Mutations in this gene cause cortical dysplasia

RGS17 Polyclonal Antibody, 100ul Bottles this protein contains an SH2This gene encodes a member of the regulator of G protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine rich region. The protein attenuates the signaling activity of G proteins by binding to activated, GTP bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta