NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation MC5R encodes a member of

MC5R encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction

implicated in a variety of cellular processes

It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process

The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation MC5R encodes a member ofProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.