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LHX4 Polyclonal Antibody, 100ul Cell Culture Flasks The hepatotrophic factor designated augmenter

SKU: 28508358706

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EUR141.00 EUR167.00

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LHX4 Polyclonal Antibody, 100ul Cell Culture Flasks The hepatotrophic factor designated augmenterThis gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine rich zinc binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4.

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Description

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver

Binding and activation of the receptor stimulates Janus protein kinases| which in turn phosphorylate several proteins| including STAT1 and STAT2

and miRNA-200b is itself downregulated in glioma tissues

providing a possible therapeutic target against neuroblastoma

LHX4 Polyclonal Antibody, 100ul Cell Culture Flasks The hepatotrophic factor designated augmenterThis gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine rich zinc binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4.

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