PDGFR alpha Polyclonal Antibody, 50ul Vacuum Filter Belongs to the Sp1 C2H2-type

Belongs to the Sp1 C2H2-type zinc-finger protein family

Polymorphisms near this gene are associated with pre-eclampsia in female human patients

Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor

This gene's protein is found in the cytoplasm| yet it lacks the nuclear localization signals found in other subfamily members

PDGFR alpha Polyclonal Antibody, 50ul Vacuum Filter Belongs to the Sp1 C2H2-typeThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in