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B2LA1 Polyclonal Antibody, 50ul Biochemical Reagents Transcription adaptor P300/CBP (EP300/CREBBP) has

SKU: 28011362280

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B2LA1 Polyclonal Antibody, 50ul Biochemical Reagents Transcription adaptor P300/CBP (EP300/CREBBP) hasThis gene encodes a member of the BCL 2 protein family. The proteins of this family form hetero or homodimers and act as anti and pro apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription

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Description

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein| which is thought to be involved in the process of blocking IFN-alpha response by adenovirus

This gene has a paralog located in the nonrecombining region of the Y chromosome

Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis

including those that are involved in familial adenomatous polyposis

B2LA1 Polyclonal Antibody, 50ul Biochemical Reagents Transcription adaptor P300/CBP (EP300/CREBBP) hasThis gene encodes a member of the BCL 2 protein family. The proteins of this family form hetero or homodimers and act as anti and pro apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription

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