Rsk-1(Phospho Ser380) Polyclonal Antibody, 50ul Mammalian Expression The gene product was initially

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

Several alternatively spliced transcript variants encoding three distinct isoforms have been reported

is a member of the ADP ribosylation factor family of ARF6 GTPase-activating proteins (GAP)

Rsk-1(Phospho Ser380) Polyclonal Antibody, 50ul Mammalian Expression The gene product was initiallyThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates including members of the mitogen activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been