Stat5 Polyclonal Antibody, 20ul[BT-AP08635] Protein Post-translational Modification Variations in the number of

Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability

Alternative splicing of SRPK1 results in multiple transcript variants

Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Interleukin-3

food intake and development

Stat5 Polyclonal Antibody, 20ul[BT-AP08635] Protein Post-translational Modification Variations in the number ofStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.