Ku-70 Polyclonal Antibody, 100ul[BT-AP04892] Cell Dissociation |PTM:Phosphorylated

|PTM:Phosphorylated

Mutations in this gene are associated with thyroid dyshormonogenesis 1

This protein is thought to regulate TRAX/Translin complex formation

The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family

Ku-70 Polyclonal Antibody, 100ul[BT-AP04892] Cell Dissociation |PTM:PhosphorylatedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with