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EI24 Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator Myosin-14 represents a conventional non-muscle

SKU: 23609103307

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EI24 Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator Myosin-14 represents a conventional non-muscleThis gene encodes a putative tumor suppressor and has higher expression in p53 expressing cells than in control cells and is an immediate early induction target of p53 mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24 a region frequently altered in cancers. Alternative splicing results in multiple transcript

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Description

Myosin-14 represents a conventional non-muscle myosin

Cathepsin L1 encoded by CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma

An important paralog of this gene is GPR45

EI24 Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator Myosin-14 represents a conventional non-muscleThis gene encodes a putative tumor suppressor and has higher expression in p53 expressing cells than in control cells and is an immediate early induction target of p53 mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24 a region frequently altered in cancers. Alternative splicing results in multiple transcript

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