p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Mutations in TPH1 have been

Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders

as a subunit of a heterodimeric complex

Expression of this gene is regulated by sterol regulatory element-binding proteins| transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids

ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45

p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Mutations in TPH1 have beenThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative