Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00864] Microplate Mixer a PDZ domain at the

a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal

nuclear localization and membrane transport

The protein encoded by TNFRSF1A (TNF receptor superfamily member 1A) is a member of the TNF-receptor superfamily

Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis

Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00864] Microplate Mixer a PDZ domain at theThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a