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CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture ZNF287 is located near the

SKU: 22200865782

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CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture ZNF287 is located near theCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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Description

ZNF287 is located near the Smith-Magenis syndrome region on chromosome 17

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

which is controlled by GTP hydrolysis-activating proteins (GAPs)

They are differentially expressed in normal tissues

CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture ZNF287 is located near theCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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