NLK Polyclonal Antibody, 20ul Drying & Desiccation ATG10 is an E2-like enzyme

ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A

which suggests a specialized role in the physiological processes underlying memory and learning abilities

Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing

Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract

NLK Polyclonal Antibody, 20ul Drying & Desiccation ATG10 is an E2-like enzymeCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by tyrosine and threonine phosphorylation (By similarity). Activated by activin.,Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt beta catenin signaling pathway and the phosphorylation and destruction of the MYB