NPHP1 Polyclonal Antibody, 20ul Protein Post-translational Modification This gene is intronless and

This gene is intronless and is clustered with CLDN8 on chromosome 21q22

which is a member of the peptidase C1 family

Four transcript variants encoding four different isoforms have been found for this gene

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases

NPHP1 Polyclonal Antibody, 20ul Protein Post-translational Modification This gene is intronless andThis gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk associated substrate, and it appears to function in the control of cell division, as well as in cell cell and cell matrix adhesion signaling, likely as part of a multifunctional complex localized in actin and microtubule based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules