DBC-1 Polyclonal Antibody, 100ul Liquid Storage Consumables Defects in this gene are

Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam

It is proposed to function in specific ubiquitin-dependent pathways

May contribute to cytokine-regulated cell proliferation and differentiation

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related

DBC-1 Polyclonal Antibody, 100ul Liquid Storage Consumables Defects in this gene areCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53