HLA Class I Polyclonal Antibody, 100ul[BT-AP10061] Pipette Micro Tips CEBPB encodes a transcription factor

CEBPB encodes a transcription factor that contains a basic leucine zipper (bZIP) domain

The five genes share a remarkably high degree of sequence identity

A mutation in this gene has been reported to be associated with hereditary spastic paraplegia| however the pathogenicity of the mutation| which may simply represent a polymorphism| is unclear

Mutations in this gene are associated with acromesomelic dysplasia

HLA Class I Polyclonal Antibody, 100ul[BT-AP10061] Pipette Micro Tips CEBPB encodes a transcription factorHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon