Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays This gene belongs to the

This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily

The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu

A mutation in this gene results in trismus-pseudocamptodactyly syndrome

This encoded protein is known as the D subunit and is found ubiquitously

Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays This gene belongs to theThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.