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SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction PTM:Phosphorylation at 'Thr-103' and 'Ser-573'

SKU: 18909264254

4.4
EUR97.20 EUR126.20

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SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction PTM:Phosphorylation at 'Thr-103' and 'Ser-573'This gene encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse

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Description

PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation

It is localized in the Down syndrome critical region of chromosome 21

and inflammatory factors

It functions as a transcriptional repressor

SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction PTM:Phosphorylation at 'Thr-103' and 'Ser-573'This gene encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse

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