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MBL-C Polyclonal Antibody, 20ul[BT-AP05258] Antibody Humanization Mutations in KRT17 lead to

SKU: 1702902432

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MBL-C Polyclonal Antibody, 20ul[BT-AP05258] Antibody Humanization Mutations in KRT17 lead toMBL2 (mannose binding lectin 2) encodes the soluble mannose binding lectin or mannose binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of MBL2 have been associated with susceptibility to autoimmune and

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Description

Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex

An important paralog of this gene is GALR2

suitable for the storage of most polar organic solutions

Caspase 3 is reported to be involved in the proteolytic processing of this protein

MBL-C Polyclonal Antibody, 20ul[BT-AP05258] Antibody Humanization Mutations in KRT17 lead toMBL2 (mannose binding lectin 2) encodes the soluble mannose binding lectin or mannose binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of MBL2 have been associated with susceptibility to autoimmune and

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