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ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Torsin-1A-interacting protein 1 localizes to

SKU: 14411760892

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ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Torsin-1A-interacting protein 1 localizes toZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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Description

Torsin-1A-interacting protein 1 localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division

which converts inositol 1

scavenger receptor cysteine-rich (SRCR) domain

The EBNA1-EBP2 interaction is important for the stable segregation of EBV episomes during cell division

ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Torsin-1A-interacting protein 1 localizes toZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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