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Bcl-2 Polyclonal Antibody, 100ul[BT-AP00860] miRNA / siRNA Synthesis which contains a FYVE zinc

SKU: 10276448445

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Bcl-2 Polyclonal Antibody, 100ul[BT-AP00860] miRNA / siRNA Synthesis which contains a FYVE zincBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

which contains a FYVE zinc finger domain and multiple WD-40 repeat domains

This protein associates constitutively with Janus kinase 2 (JAK2)

The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif

2003 [PubMed 14519125])

Bcl-2 Polyclonal Antibody, 100ul[BT-AP00860] miRNA / siRNA Synthesis which contains a FYVE zincBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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